Title of article
Unique Presentation of Rosai-Dorfman Disease as ConcomitantAppendiceal and Rectal Masses with IgG4-Positive Plasma CellsDiagnosed by Core Needle Biopsy
Author/Authors
Makramalla, Abouelmagd University of Cincinnati Medical Center, USA , Poldemann, Jenna J. University of Cincinnati Medical Center, USA , Hinrichs, Benjamin H. University of Cincinnati Medical Center, USA
Pages
5
From page
1
To page
5
Abstract
Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a rare non-Langerhans cell histiocytosis.We report a case of a 69-year-old male with concurrent appendiceal and rectal masses who underwent CT-guided percutaneousbiopsy. Histopathology confirmed a diagnosis of RDD with IgG4-positive plasma cells. It is believed to be a subset of RDD thatshares similar features with IgG4-related disease suggesting some overlap of the two diseases. Because gastrointestinal RDDaccounts for less than 1% of extranodal disease, it is important to recognize this entity in order to guide management. Wereview the presentation, diagnosis, and treatment of gastrointestinal RDD and discuss the possible overlap with IgG4-relateddisease.
Keywords
Unique Presentation , Rosai-Dorfman Disease , Concomitant Appendiceal , Rectal Masses , IgG4-Positive Plasma Cells Diagnosed , Core Needle Biopsy , RDD
Journal title
Case Reports in Oncological Medicine
Serial Year
2020
Record number
2608485
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