Title of article :
Efficient synthesis of N-amino pyridine-2,6-diones via a novel one-pot, the three-component reaction between 2-cyanoacetohydrazide, Meldrum's acid, and aryl aldehyde
Author/Authors :
Asadi, S. Department of Chemistry - Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran , Alizadeh-Bami, F. Department of Chemistry - Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran , Mehrabi, H. Department of Chemistry - Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran
Abstract :
A new and efficient approach has been developed for the synthesis of N-amino pyridine-2,6-dione derivatives by a one-pot, three-component reaction of 2-cyanoacetohydrazide, Meldrum's acid, and aryl aldehyde in the presence of piperidine in DMF. All the products were obtained in excellent yields and their structures were established from their spectroscopic data.
Keywords :
2-Cyanoacetohydrazide , Meldrum's acid , Aryl aldehyde , N-Amino pyridine-2 , 6-dione
Journal title :
Organic Chemistry Research
