Why Children are Less Likely to Contract COVID‑19 Infection than Adults?

The novel coronavirus disease of 2019 (COVID‑19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2).[1] The reported cases of COVID‑19 among children have been less severe than those in adults.[2] Dong et al.,[3] in a recent clinical study of more than 2000 infants and preschool‑aged children with suspected COVID‑19, found that 4% of virologically confirmed cases were symptomatic and among children who were symptomatic, 5% experienced dyspnea and hypoxemia, and only 0.6% progressed to acute respiratory distress syndrome, a substantially lower percentage rate than has been reported in adults.