Title of article :
Numerical and Experimental Investigation of Novel Blended Bifurcated Stent Grafts with Taper to Improve Hemodynamic Performance
Author/Authors :
Liu, Ming School of Biological Science and Medical Engineering - Beihang University - Beijing, China , Wang, Zhenze Ronghuazhong Road - Beijing BDA - Beijing, China , Sun, Anqiang School of Biological Science and Medical Engineering - Beihang University - Beijing, China , Deng, Xiaoyan School of Biological Science and Medical Engineering - Beihang University - Beijing, China
Abstract :
+e typical helical flow within the human arterial system is widely used when designing cardiovascular devices, as this helical flow
can be generated using the “crossed limbs” strategy of the bifurcated stent graft (BSG) and enhanced by the tapered structure of
arteries. Here, we propose the use of a deflected blended bifurcated stent graft (BBSG) with various tapers, using conventional
blended BSGs with the same degree of taper as a comparison. Hemodynamic performances, including helical strength and wall
shear stress- (WSS-) based indicators, were assessed. Displacement forces that may induce stent-graft migration were assessed
using numerical simulations and in vitro experiments. +e results showed that as the taper increased, the displacement force,
helicity strength, and time-averaged wall shear stress (TAWSS) within the iliac grafts increased, whereas the oscillating shear index
(OSI) and relative residence time (RRT) gradually decreased for both types of BBSGs. With identical tapers, deflected BBSGs,
compared to conventional BBSGs, exhibited a wider helical structure and lower RRT on the iliac graft and lower displacement
force; however, there were no differences in hemodynamic indicators. In summary, the presence of tapering facilitated helical flow
and produced better hemodynamic performance but posed a higher risk of graft migration. Conventional and deflected BBSGs
with taper might be the two optimal configurations for endovascular aneurysm repair, given the helical flow. +e deflected BBSG
provides a better configuration, compared to the conventional BBSG, when considering the reduction of migration risk.
Keywords :
Hemodynamic , risk , BBSG , TAWSS
Journal title :
Computational and Mathematical Methods in Medicine