Author/Authors :
Yamamoto, Shinya Department of Breast Surgery - Fujisawa City Hospital - Fujisawa City - Kanagawa , Japan , Yamagishi, Shigeru Department of Breast Surgery - Fujisawa City Hospital - Fujisawa City - Kanagawa , Japan , Kohno, Toshiro Shonan Fujisawa Clinic - Hanazawa-cho, Kugenuma - Fujisawa City - Kanagawa , Japan , Tajiri, Ryosuke Department of Diagnostic Pathology - Fujisawa City Hospital - Fujisawa City - Kanagawa , Japan , Gondo, Toshikazu Department of Diagnostic Pathology - Fujisawa City Hospital - Fujisawa City - Kanagawa , Japan , Yoshimoto, Noboru Department of Thoracic Surgery - Fujisawa City Hospital - Fujisawa - Fujisawa City - Kanagawa , Japan , Kusano, Nobuko Ambulatory Treatment Center - Fujisawa City Hospital - Fujisawa, - Kanagawa , Japan
Abstract :
Malignant phyllodes tumors of the breast occur infrequently and are difficult to treat with chemotherapy. Here, we present aneffective chemotherapy strategy for recurrent malignant breast phyllodes tumors. A 48-year-old woman was diagnosed with amalignant phyllodes tumor in her right breast and underwent total right mastectomy. One year later, the tumor recurred in theright (a 2.2 cm mass) and left (a 10 cm mass) lungs; pleural effusion was also observed in the left lung. Eight courses ofdoxorubicin-ifosfamide (AI) therapy were administered. After treatment, the right lung mass and pleural effusion regressedcompletely and the left lung mass regressed to 2 cm. In conclusion, AI therapy is useful for treating recurrent malignant breastphyllodes tumors
