Author/Authors :
Kuno, Toshiki Department of Cardiology - Japanese Red Cross Ashikaga Hospital, Ashikaga, Japan , Imaeda, Syohei Department of Cardiology - Japanese Red Cross Ashikaga Hospital, Ashikaga, Japan , Asakawa, Yohei Department of Neurology - Japanese Red Cross Ashikaga Hospital, Ashikaga, Japan , Nakamura, Hiroshi Department of General Internal Medicine - Hiroshima-Nishi Medical Center, Ohtake, Japan , Takemura, Genzou Department of Internal Medicine - Asahi School of Dentistry University, Mizuho, Japan , Asahara, Daisuke Department of Neurology - Japanese Red Cross Ashikaga Hospital, Ashikaga, Japan , Kanamori, Akira Department of Gastroenterology - Japanese Red Cross Ashikaga Hospital, Ashikaga, Japan , Kabutoya, Tomoyuki Department of Cardiology - Jichi Medical University, Shimotsuke, Japan , Numasawa, Yohei Department of Cardiology - Japanese Red Cross Ashikaga Hospital, Ashikaga, Japan
Abstract :
We report a case with 46-year-old man diagnosed with mitochondrial cardiomyopathy in the dilated phase of hypertrophic cardiomyopathy. Since cardiac magnetic resonance imaging, beta-methyl-p-123I-iodophenyl-pentadecanoic myocardial scintigraphy,
and positron emission tomography/computed tomography revealed no remarkable findings, we performed electron microscopic
examination, which aided in diagnosing mitochondrial cardiomyopathy. Muscle biopsy was also compatible with mitochondrial
encephalomyopathy, lactic acidosis, and stroke-like episodes and DNA analysis also concluded it. Since muscle biopsy is less invasive
for patients compared to endomyocardial biopsy, cardiologists need to consider it. The diagnosis of mitochondrial cardiomyopathy
is helpful because it is a genetic condition and also for consideration of device therapy, as well as management for acute crisis.
