Author/Authors :
Maljaei, Mohammad Bagher Department of Nutrition - School of Public Health - Iran University of Medical Sciences, Isfahan, Iran , Moradi, Maedeh Food Security Research Center and Department of Community Nutrition - School of Nutrition and Food Science - Isfahan University of Medical Sciences, Isfahan, Iran , Tarbiat Nobari, Nazanin Department of Nutrition - Faculty of Medicine - Zahedan University of Medical Sciences, Zahedan, Iran , Bahreini, Asma Isfahan Neuroscience Research Center - Alzahra Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Namjoo, Iman Isfahan Neuroscience Research Center - Alzahra Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran
Abstract :
Multiple sclerosis (MS) is a chronic neurological disease
characterized by inflammation and development of
demyelinating central nerve system which occurs mostly
in young adults and is more prevalent in females. The
definite etiology of MS is unknown but interacting
genetic and environmental factors are considered to be
involved in its pathogenesis. Among environmental factors
affecting the prognosis of the disease, recent investigations
have shed the light on the role of vitamin B12, folate,
and homocysteine (Hcy) as possible determinants of
the progressive neurodegenerative process.
