Author/Authors :
Kantor, Micaella Kendall Regional Medical Center, Miami, USA , Abrantes, Anarella Kendall Regional Medical Center, Miami, USA , Estevez, Andrea Kendall Regional Medical Center, Miami, USA , Schiller, Alan Kendall Regional Medical Center, Miami, USA , Torrent, Jose Kendall Regional Medical Center, Miami, USA , Gascon, Jose Kendall Regional Medical Center, Miami, USA , Hernandez, Robert Kendall Regional Medical Center, Miami, USA , Ochner, Christopher Hospital Corporation of America - East Florida Division, Fort Lauderdale, USA
Abstract :
Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected with E. histolytica remain asymptomatic, some present with amoebic colitis and disseminated disease. As more is learned about its pathogenesis and the host's immune response, the potential for developing a vaccine holds promise. This narrative review outlines the current knowledge regarding E. histolytica and E. dispar and insight in the development of a vaccine.
