Author/Authors :
Abdel-Rahman, Omar Clinical Oncology Department - Faculty of Medicine, Ain Shams University, Cairo, Egypt , Cheung, Winson Y Department of Oncology - University of Calgary - Tom Baker Cancer Centre, Alberta, Canada
Abstract :
Hepatocellular carcinoma (HCC) represents a global health problem, with the majority of patients presenting at an advanced or incurable stage. The development of effective systemic therapy options for this disease has been challenging because many HCC patients suffer from underlying liver cirrhosis that precludes the safe delivery of systemic therapy. The current review seeks to provide an overview of the current systemic therapeutic approaches for advanced HCC as well as some of the novel management strategies that are currently being evaluated.
