Title of article :
Malignant Phyllodes Tumor of the Breast with Metastasis to thePancreas: A Case Report and Review of Literature
Author/Authors :
Amir, R.A Imam Abdulrahman Bin Faisal University - Dhahran, Saudi Arabia , Rabah, Rola S. Pathology Services Division- Johns Hopkins Aramco Healthcare - Dhahran, Saudi Arabia , Sheikh, S.S Pathology Services Division- Johns Hopkins Aramco Healthcare - Dhahran, Saudi Arabia
Abstract :
Phyllodes tumor (PT) is a rare tumor of the breast accounting for approximately 1% of all breast neoplasms. In 1838, J. Mullercoined the term“cystosarcoma phyllodes”based on the leaf-like projections of the tumor extending into the cystic spaces andsarcomatous stromal growth. However, seeing as up to 70% of phyllodes tumors are benign,“cystosarcoma”was removed, andthe tumor is now recognized simply as phyllodes tumor. It is mainly seen in females between the ages of 35 and 55. Althoughmost phyllodes tumors are benign, malignant cases do uncommonly occur, 22% of which have distant metastasis typically to thelungs and bones. Rarely, this tumor metastasizes to other locations. Herein, we report a case of malignant phyllodes tumor withmetastasis to the pancreas. According to our knowledge, only 3 case reports of pancreatic metastasis from malignant phyllodestumor have been reported in literature thus far. We aim to increase awareness among physicians of this rare metastasic potentialof the uncommonly encountered malignant phyllodes tumor
Keywords :
Malignant Phyllodes Tumor , Breast , Metastasis , Pancreas , Phyllodes tumor (PT)
Journal title :
Case Reports in Oncological Medicine