Metastatic Sarcomatoid Squamous Cell Carcinoma ofthe Cervix Presenting with Chest Mass

Sarcomatoid squamous cell carcinoma is a rare and aggressive form of cervical cancer. We report a case of metastaticsarcomatoid squamous cell carcinoma (SSCC) of cervix that presented with an anterior chest wall mass.Case.A43-year-oldHispanic female presented with a two-month history of a central chest wall mass. The patient’s only past medical history was SSCCof the cervix, stage IIB, diagnosed two years priorly. She underwent neoadjuvant chemoradiation therapy (CRT) with cisplatinfollowed by radical hysterectomy. Surgical margins were positive which led to adjuvant CRT with carboplatin and paclitaxel. PETscan 4 months after the postoperative treatment was negative for recurrence and metastatic disease. On current presentation, theCT chest revealed anterior mediastinal destructive soft tissue mass involving sternum, and the biopsy showed SSCC. The patientreceived palliative radiation therapy to her chest with improvement in pain and ability to swallow. After discussing the prognosisshe refused further chemotherapy and decided on hospice care.Conclusion. Despite good response to first-line therapy, SSCC tendsto recur early and does not respond to second-line therapy. Radiation therapy seems to be the most effective modality for treatment,but randomized controlled trials of therapy are impractical.