All That Wheezes Is Not Asthma: A Case of Diffuse LargeB-Cell Lymphoma of the Larynx

Localizedlaryngeallymphomaisarareentitywithanincidenceoflessthan1%ofalllaryngealneoplasms.DiffuselargeB-celllymphoma (DLBCL) is the most common type of laryngeal neoplasms. Here, we describe a case of a young 28-year-old femalewith large B-cell lymphoma who remained undiagnosed for a long time owing to a myriad of nonspecific presentation including“wheezing.” Although primary laryngeal lymphomas constitute a diagnostic challenge since they are rare, one should have a highindex of suspicion for lymphoma of the larynx in patients presenting with unresolved wheezing as it can present catastrophicallywith acute airway obstruction requiring immediate surgical intervention which was observed in this case. Treatment includesradiotherapy, chemotherapy, immunotherapy, or a combination of these. We hope that the discussions ensuing from case reportsregarding uncommon presentations of laryngeal lymphoma may spur the formation of regional/international databases for thedescription of lymphomas with unusual presentations. This effort can lead to in-depth study of cases and prompt awareness of“rare and subtle presentations” of laryngeal lymphoma.