Author/Authors :
Khan, Maliha Department of Leukemia - The University of Texas MD Anderson Cancer Center - Houston - TX, USA , Korphaisarn, Krittiya Department of Gastrointestinal Medical Oncology - The University of Texas MD Anderson Cancer Center- Houston - TX, USA , Saif, Aneeqa Department of Internal Medicine - Dow University of Health Sciences - Karachi, Pakistan , Foo, Wai C. Department of Pathology - The University of Texas MD Anderson Cancer Center - Houston - TX, USA , Kopetz, Scott Department of Gastrointestinal Medical Oncology - The University of Texas MD Anderson Cancer Center- Houston - TX, USA
Abstract :
Colorectal cancer (CRC) remains the second leading cause of cancer-related deaths in the United States. While a decline has beenobserved in the older population, the occurrence of CRC in the adolescent and young adult (AYA) population has increased over thepast two decades. The histopathologic characteristics and clinical behavior of CRC in AYA patients have been shown to be distinctfrom those of CRC in older adults. The rarer subtypes of CRC such asmucinous adenocarcinoma and signet-ring cell carcinoma areassociated with a poorer prognosis compared to the more common subtypes. Here we report a case of a 20-year-old man who wasdiagnosed with stage IVB (T4 N2 M1, with peritoneal carcinomatosis) signet-ring cell adenocarcinoma of the colon. The scarcityof information on these rarer subtypes merits further study and investigation
Keywords :
Early-Onset , Signet-Ring , Cell Adenocarcinoma , Colon , AYA , IVB , Colorectal cancer (CRC)
