Angiomyolipoma and Malignant PEComa: Discussion of TwoRare Adrenal Tumors

Angiomyolipoma and PEComa are rare tumors descending from perivascular epithelial cells (PECs), with distinctive IHC,morphological, and ultrastructural features. The kidney is the most frequent site of origin, but not the only one; however, adrenalgland angiomyolipomas are extremely rare. We describe two cases being found in the adrenal glands. Given the paucity of literatureon the subject, more information on this disease is necessary for diagnosis and treatment. Here, we describe two complete casereports, from presentation to treatment and follow-up, along with imaging and microscopic pathology samples, and provide acomprehensive review as to the history and current literature available regarding these extremely rare tumors