Title of article :
Capecitabine Induced Multifocal Leukoencephalopathy:Do We Have Always to Switch off the Chemotherapy ?
Author/Authors :
Andreadou, Elisabeth Department of Neurology - National and Kapodistrian University of Athens Medical School - Eginition Hospital - Athens, Greece , Bougea, Anastasia Department of Neurology - National and Kapodistrian University of Athens Medical School - Eginition Hospital - Athens, Greece , Voskou, Panagiota Department of Neurology - National and Kapodistrian University of Athens Medical School - Eginition Hospital - Athens, Greece , Kilidireas, Constantinos Department of Neurology - National and Kapodistrian University of Athens Medical School - Eginition Hospital - Athens, Greece
Abstract :
Capecitabine is a well tolerated and safe 5-fluorouracil agent for adjuvant, neoadjuvant chemotherapy or metastatic cases.Neurological side effects require discontinuation of chemotherapy. We report this unique case of a 50-year-old female, whopresented an isolated episode of dysarthria and ataxia under bevacizumab, capecitabine, and oxaliplatin treatment due to reversiblemultifocal leukoencephalopathy that did not recur after readministration of chemotherapy
Keywords :
Capecitabine Induced Multifocal Leukoencephalopathy , Switch off the Chemotherapy , 5-Fluorouracil (5-FU)
Journal title :
Case Reports in Oncological Medicine
