مرکز منطقه ای اطلاع رساني علوم و فناوري - A Case of Eosinophilic Granulomatosis with PolyangiitisComplicated with A IgG4 Related Disease Like Symptoms

Author/Authors :

Shibata, Yoko Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Sato, Suguru Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Morimoto, Julia Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Umeda, Takashi Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Kawamata, Takaya Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Rikimaru, Mami Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Koizumi, Tatsuhiko Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Togawa, Ryuichi Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Suzuki, Yasuhito Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Sato, Yuki Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Uematsu, Manabu Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Minemura, Hiroyuki Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Nikaido, Takefumi Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Fukuhara, Atsuro Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Saito, Junpei Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Kanazawa, Kenya Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Tanino, Yoshinori Department of Pulmonary Medicine - School of Medicine - Fukushima Medical University - Fukushima, Japan , Oguchi, Yasuharu Department of Ophthalmology - School of Medicine - Fukushima Medical University - Fukushima, Japan , Munakata, Mitsuru Department of Infectious Disease and Pulmonary Medicine - Aizu Medical Center - Fukushima Medical University - Aizuwakamatsu, Japan

Abstract :

We report a case of eosinophilic granulomatosis with polyangiitis (EGPA) complicated with a IgG4 related disease like symptomspresenting as eyelid swellings. In the present case, the serum level of IgG4 and the ratio of IgG4 to IgG were generally increasedby the disease course of EGPA. Considering the course of clinical symptoms, there is a possibility that orbital manifestations wereone of the clinical features during the disease course of EGPA while the histological features of right eyelid tissue and other ocularmanifestations were consistent with the diagnosis of IgG4 related disease