Author/Authors :
Miao, Zhiguo College of Animal Science and Veterinary Medicine - Henan Institute of Science and Technology, Henan , China , Wang, Shan College of Animal Science and Veterinary Medicine - Henan Institute of Science and Technology, Henan , China , Wang, Yimin College of Animal Science and Veterinary Medicine - Henan Institute of Science and Technology, Henan , China , Guo, Liping College of Animal Science and Veterinary Medicine - Henan Institute of Science and Technology, Henan , China , Zhang, Jinzhou College of Animal Science and Veterinary Medicine - Henan Institute of Science and Technology, Henan , China , Liu, Yang College of Animal Science and Veterinary Medicine - Henan Institute of Science and Technology, Henan , China , Yang, Qiyuan Department of Molecular - Cell and Cancer Biology - University of Massachusetts Medical School, Worcester, USA
Abstract :
Vitamin D has been discovered centuries ago, and current studies have focused on the biological effects of vitamin D on adipogenesis. Besides its role in calcium homeostasis and energy metabolism, vitamin D is also involved in the regulation of development and process of metabolic disorders. Adipose tissue is a major storage depot of vitamin D. This review summarized studies on the relationship between vitamin D and adipogenesis and furthermore focuses on adipose metabolic disorders. We reviewed the biological roles and functionalities of vitamin D, the correlation between vitamin D and adipose tissue, the effect of vitamin D on adipogenesis, and adipose metabolic diseases. Vitamin D is associated with adipogenesis, and vitamin D supplements can reduce the burden caused by metabolic diseases. The review provides new insights and basis for medical therapy on adipose metabolic diseases.
