Author/Authors :
Alejandro Rivillas, Julián Resident of Neurology - Universidad Icesi, Cali, Colombia , Galindo-Coral, Stephania Cardiology Department - Fundación Valle del Lili Hospital Universitario, Cali, Colombia , Arias-Mora, Francisco Neurology Department - Fundación Valle del Lili Hospital Universitario, Cali, Colombia , Lopez-Ponce de Leon, Juan David Cardiology Department - Fundación Valle del Lili Hospital Universitario, Cali, Colombia , Florez-Alarcón, Noel Alberto Cardiology Department - Fundación Valle del Lili Hospital Universitario, Cali, Colombia , Olaya-Rojas, Pastor Cardiology Department - Fundación Valle del Lili Hospital Universitario, Cali, Colombia , Gomez-Mesa, Juan Esteban Cardiology Department - Fundación Valle del Lili Hospital Universitario, Cali, Colombia
Abstract :
Background. Neurological complications occur between 50 and 70% of patients with heart transplantation, including
cerebrovascular events, infections, seizures, encephalopathy, and neurotoxicity due to pharmacological immunosuppression.
Mortality associated with cerebrovascular complications is 7.5% in the first 30 days and up to 5.3% after the first month and up
to the first year after transplantation. Case Reports. Three heart-transplanted patients (2 men and 1 woman) treated with
tacrolimus were identified. They presented with posterior reversible encephalopathy syndrome on days 5, 6, and 58
posttransplantation, respectively. In these reported cases, no sequelae were observed at 6 months follow-up. Conclusions.
Posterior reversible encephalopathy syndrome as a neurological complication in patients with HT occurred early after the
procedure. Early diagnosis and treatment might reduce the risk of serious complications and mortality
Keywords :
Posterior Reversible Encephalopathy , Syndrome , Tacrolimus , Cardiac Transplantation
