Author/Authors :
Liu, Chen Department of Materials Science and Engineering - Zhejiang University - Hangzhou, China , Zhao, Xinbing Department of Materials Science and Engineering - Zhejiang University - Hangzhou, China , Ren, Zheng Ningbo Branch of China Academy ofOrdnance Science - Ningbo, China , Xu, Yongdong Ningbo Branch of China Academy ofOrdnance Science - Ningbo, China , Pang, Song Ningbo Branch of China Academy ofOrdnance Science - Ningbo, China , Zhao, Ying Shenzhen Institutes of Advanced Technology - Chinese Academy of Sciences - Shenzhen, China
Abstract :
Bone repair materials are rapidly becoming a hot topic in the field of biomedical materials due to being an importantmeans of repairing human bony deficiencies and replacing hard tissue. Magnesium (Mg) alloys are potentially biocompatible,osteoconductive, and biodegradable metallic materials that can be used in bone repair due to their in situ degradation in the body,mechanical properties similar to those of bones, and ability to positively stimulate the formation of new bones. However, rapiddegradation of these materials in physiological environments may lead to gas cavities, hemolysis, and osteolysis and thus, hindertheir clinical orthopedic applications. This paper reviews recent work on the use of Mg alloy implants in bone repair. Researchto date on alloy design, surface modification, and biological performance of Mg alloys is comprehensively summarized. Futurechallenges for and developments in biomedical Mg alloys for use in bone repair are also discussed
