Title of article :
Alpinia Essential Oils and Their Major Components against Rhodnius nasutus, a Vector of Chagas Disease
Author/Authors :
de Souza, Thamiris de A Faculty of Pharmacy - Federal Fluminense University - Rua Doutor Mario Viana 523 - Santa Rosa - Niter ´ oi - RJ - Brazil - Laboratory of Medicinal Plants and Derivatives - Department of Chemistry of Natural Products - Farmanguinhos - FIOCRUZ - Rio de Janeiro - RJ - Brazil , Lopes, Marcio B. P Laboratory of Medical and Forensic Entomology - IOC - FIOCRUZ - Av. Brasil 4365 - Rio de Janeiro - RJ - Brazil , Ramos, Aline de S Laboratory of Medicinal Plants and Derivatives - Department of Chemistry of Natural Products - Farmanguinhos - FIOCRUZ - Rio de Janeiro - RJ - Brazil , Ferreira, José Luiz P Faculty of Pharmacy - Federal Fluminense University - Rua Doutor Mario Viana 523 - Santa Rosa - Niter ´ oi - RJ - Brazil - Laboratory of Medicinal Plants and Derivatives - Department of Chemistry of Natural Products - Farmanguinhos - FIOCRUZ - Rio de Janeiro - RJ - Brazil , Silva, Jefferson Rocha de A Chromatography Laboratory - Chemistry Department - Federal University of Amazonas - Manaus - AM - Brazil , Queiroz, Margareth M. C Laboratory of Medical and Forensic Entomology - IOC - FIOCRUZ - Av. Brasil 4365 - Rio de Janeiro - RJ - Brazil , de Lima Araújo, Kátia G Faculty of Pharmacy - Federal Fluminense University - Rua Doutor Mario Viana 523 - Santa Rosa - Niter ´ oi - RJ - Brazil , Amaral, Ana Claudia F Laboratory of Medicinal Plants and Derivatives - Department of Chemistry of Natural Products - Farmanguinhos - FIOCRUZ - Rio de Janeiro - RJ - Brazil
Abstract :
Species of the genus Alpinia are widely used by the population and have many described biological activities, including activity against insects. In this paper, we describe the bioactivity of the essential oil of two species ofAlpinia genus,A. zerumbet andA. vittata, against Rhodnius nasutus, a vector of Chagas disease. The essential oils of these two species were obtained by hydrodistillation and
analyzed by GC-MS. The main constituent of A. zerumbet essential oil (OLALPZER) was terpinen-4-ol, which represented 19.7% of the total components identified. In the essential oil of A. vittata (OLALPVIT) the monoterpene 𝛽-pinene (35.3%) was the main
constituent. The essential oils and their main constituents were topically applied on R. nasutus fifth-instar nymphs. In the first
10 min of application, OLALPVIT and OLALPZER at 125 𝜇g/mL provoked 73.3% and 83.3% of mortality, respectively. Terpinen-4-
ol at 25 𝜇g/mL and 𝛽-pinene at 44 𝜇g/mL provoked 100% of mortality.The monitoring of resistant insects showed that both essential
oils exhibited antifeedant activity. These results suggest the potential use of A. zerumbet and A. vittata essential oils and their major constituents to control R. nasutus population.
Keywords :
Alpinia Essential Oils , against Rhodnius nasutus, , Chagas Disease , Vector , OLALPVIT , OLALPZER
Journal title :
The Scientific World Journal
