Author/Authors :
Camargo Moraes, Paulo de Department of Oral Surgery - School of Dentistry, SLMandic, Campinas, SP, Brazil , Alexandre Thomaz, Luiz Department of Oral Radiology - School of Dentistry, SLMandic, Campinas, SP, Brazil , Martins Montalli, Victor Angelo Department of Oral Pathology - School of Dentistry, SLMandic, Campinas, SP, Brazil , Cintra Junqueira, José Luiz Department of Oral Radiology - School of Dentistry, SLMandic, Campinas, SP, Brazil , Beder Ribeiro, Camila Maria Department of Oral Pathology and Stomatology, FOP-UNICAMP, Piracicaba, SP, Brazil , Butini Oliveira, Luciana Department of Oral Radiology - School of Dentistry, SLMandic, Campinas, SP, Brazil
Abstract :
The aim of this paper is to describe a case report of EMP in an HIV-positive patient. A 44-year-old, dark-skinned HIV-infected
woman was referred to the Oral Diseases Treatment Center with a swelling at palate and left gingival fornix in the maxilla. Biopsy
was taken and the oral lesion was diagnosed as EMP with well-differentiated plasma cells and restriction of the lambda lightchain. Skeletal survey was performed and no radiograph alterations were observed, thus supporting the diagnosis of EMP. Patient
was referred to treatment and after two months of chemo and radiotherapy, an expanding lesion was observed in L5/S1 patient’s
vertebrae. Biopsy of the spinal lesion was consistent with lymphoma with plasmocitary differentiation, supporting the diagnosis of
multiple myeloma (MM). Regarding the medical history, the final diagnostic was an oral extramedullary plasmacytoma with rapid
progression into multiple myeloma. It is crucial to emphasize the relevance of HIV infection as a risk factor for both aggressive
clinical behavior and unusual clinical presentation of extramedullary plasmacytoma cases.
