Author/Authors :
de Abreu, Taciana Cavalcanti Universidade de Pernambuco (UPE), Recife-PE, Brazil , de Lima, Rodrigo Pontes Department of Surgery - UFPE, Recife-PE, Brazil , de Souza, Veridiana Sales Barbosa Department of Surgery - Universidade Federal de Pernambuco (UFPE), Recife-PE, Brazil , Júnior, Olavio Campos Department of Anatomy - UFPE, Recife-PE, Brazil , de Albuquerque, Amanda Vasconcelos Department of Surgery - UFPE, Recife-PE, Brazil , de Andrade Aguiar, José Lamartine Department of Surgery - UFPE, Recife-PE, Brazil , Andrade, Emanuel Sávio de Souza Department of Oral and Maxillofacial Surgery and Traumatology Subject - UPE, Recife-PE, Brazil , Vasconcelos, Belmiro Cavalcanti do Egito Department of Oral and Maxillofacial Surgery and Traumatology Subject - UPE, Recife-PE, Brazil
Abstract :
PURPOSE: To evaluate the effects of particulate (granule-shaped) SCB on bone repair relating it to its biocompatibility and bone neoformation.
METHODS: Thirty Wistar rats were submitted to a one 7-mm-diameter defect and divided equally into three experimental groups, with two different postoperative times of evaluation, 90 and 120 days. Each calvaria defect was filled up with clot (control group), particulated autogenous bone or granulated SCB. Five animals of each group were assessed at 90 and 120 days after surgery. In these two periods, histological and histometric analysis were obtained.
RESULTS: The clot group showed a bone resorption trend while the autogenous bone group a bone repair trend. However in the SCB group, the critical defect filled up only with fibrous connective tissue and presented none bone neoformation.
CONCLUSION: The sugarcane biopolymer when used in critical size defects was a biocompatible material and proved to be a good material to fill bone cavities, keeping them as uniform areas filled with soft tissue and avoiding the tissue shrinkage.
Keywords :
Biopolymers , Bone Regeneration , Bone Transplantation , Dental Implants , Rats
