Author/Authors :
Pinheiro, Cristiane Lima Department of Surgery - School of Medicine - Universidade Federal do Rio de Janeiro (UFRJ), Brazil , Peixinho, Carolina Carneiro COPPE - UFRJ, Rio de Janeiro-RJ, Brazil , Esposito, Cristiano Costa Department of Surgery - School of Medicine - UFRJ, Rio de Janeiro-RJ, Brazil , Manso, José Eduardo Ferreira Department of Surgery - School of Medicine - UFRJ, Rio de Janeiro-RJ, Brazil , Machado, João Carlos Department of Surgery - School of Medicine and Biomedical Engineering Program - COPPE - UFRJ, Rio de Janeiro-RJ, Brazil
Abstract :
PURPOSE:
To track the regeneration process of lateral gastrocnemius due to a muscle laceration in rats, and to treatment with plateletrich plasma (PRP).
METHODS:
Ultrasound (40 MHz) images were used for measuring pennation angle (PA), muscle thickness (MT) and mean pixel intensity, along with claudication scores, of treated (PRPG) and non-treated (NTG) groups of rats.
RESULTS:
NTG showed a PA increase for the non-injured leg (p<0.05) and a tendency of MT to increase, whereas for PRPG there were no differences. There was a progressive reduction of the claudication score for the PRPG group throughout the entire period, with an immediate difference after seven days (p<0.05), whereas the NTG had a significant reduction only at day 28 (p<0.05).
CONCLUSION:
It was observed a compensatory hypertrophic response due to the overload condition imposed to healthy leg for NTG that did not occur in PRPG, suggesting an accelerated repair process of the injured leg due to treatment, anticipating its use.
Keywords :
Ultrasonography , Platelet-Rich Plasma , Soft Tissue Injuries , Rats
