Title of article :
Aging delay: of mice and men
Author/Authors :
Anisimov, Vladimir N. Department of Carcinogenesis and Oncogerontology - Petrov National Medical Research Center of Oncology, Pesochny, St. Petersburg, Russia
Abstract :
The evaluation of the safety of a drug in rodents that may be used as geroprotectors is a challenge of current times. In the paper, we discuss approaches to long-term assays for selection of potent aging delay drugs for humans. Priority is given to methods combining evaluation of carcinogenic safety and life-spanning potential. The use of such methods will be time-efficient and economically feasible. (www.actabiomdica.it)
Keywords :
Geroprotectors , testing , rodents , humans
Journal title :
Acta bio-medica : Atenei Parmensis
