Title of article
Crystal structures of (S)-(+)-5-(3-bromo/chloro-4-isopropoxyphenyl)-5-methylimidazolidine-2,4-dione
Author/Authors
Ohba, Shigeru Research and Education Center for Natural Sciences - Keio University, Japan , Koura, Minoru Tokyo New Drug Research Laboratories - Pharmaceutical Division - Kowa Company, Japan , Sumida, Hisashi Tokyo New Drug Research Laboratories - Pharmaceutical Division - Kowa Company, Japan , Shibuya, Kimiyuki Tokyo New Drug Research Laboratories - Pharmaceutical Division - Kowa Company, Japan
Pages
12
From page
1
To page
12
Abstract
In (S)-(+)-5-(3-bromo-4-isopropoxyphenyl)-5-methylimidazolidine-2,4-dione, C13H15BrN2O3, (I), the hydantoin groups are connected via intermolecular N—H⋯O hydrogen bonds, forming a terraced sheet structure. In the chloro analogue, (S)-(+)-5-(3-chloro-4-isopropoxyphenyl)-5-methylimidazolidine-2,4-dione, C13H15ClN2O3, (II), the intermolecular N—H⋯O hydrogen-bonding network forms a flat sheet. Comparison of the crystal structures reveals that (II) is more loosely packed than (I)
Keywords
crystal structure , hydantoin , hydrogen bonding , absolute configuration
Journal title
Acta Crystallographica Section E: Crystallographic Communications
Serial Year
2016
Record number
2614606
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