Author/Authors :
Amélia Souza, Ana Department of Oral Pathology - Sao Leopoldo Mandic Institute and Research Center, SP, Brazil , Guttenberg Cariri Neto, Eldon Department of Oral Pathology - Sao Leopoldo Mandic Institute and Research Center, SP, Brazil , Cavalcanti de Araújo, Vera Department of Oral Pathology - Sao Leopoldo Mandic Institute and Research Center, SP, Brazil , Passador-Santos, Fabricio Department of Oral Pathology - Sao Leopoldo Mandic Institute and Research Center, SP, Brazil , Teresa de Seixas Alves, Maria Department of Pathology, Escola Paulista de Medicina, Rua Botucatu, Vila Clementino, Sao Paulo, SP, Brazil , Borges Soares, Andresa Department of Oral Pathology - Sao Leopoldo Mandic Institute and Research Center, SP, Brazil
Abstract :
This report describes a rare case of nodular fasciitis (NF) of the oral cavity, discussing the clinical, histological, and
immunohistochemical characteristics. Histopathologic diagnosis of this type of lesion can be challenging due to its differential
diagnosis, which principally includes sarcoma. The patient presented with a painless, well-defined nodule, reported as increasing in
size, located at the apical aspect of the upper left buccal sulcus. Histologically, the lesion revealed spindle cell proliferation arranged
in fascicles, while immunohistochemistry demonstrated positivity for smooth muscle actin. Eight months after complete surgical
excision, no signs of local recurrence have been observed.
