Author/Authors :
Motta, Ilse Sodré Botucatu Medical School - Universidade Estadual Paulista (UNESP), Botucatu-SP, Brazil , Volpato, Gustavo Tadeu University Center of Araguaia - Universidade Federal do Mato Grosso (UFMT), Barra do Garças-MT, Brazil , Damasceno, Débora Cristina Botucatu Medical School - UNESP, Botucatu-SP, Brazil , Sinzato, Yuri Karen Botucatu Medical School - UNESP, Botucatu-SP, Brazil , Vesentini, Giovana Botucatu Medical School - UNESP, Botucatu-SP, Brazil , Rudge, Cibele Vieira Cunha Botucatu Medical School - UNESP, Botucatu-SP, Brazil. , Calderon, Iracema Mattos Paranhos Botucatu Medical School - UNESP, Botucatu-SP, Brazil. , Kempinas, Wilma De Grava Department of Morphology - UNESP, Botucatu-SP, Brazil , Odland, Jon Øvid Department of Community Medicine - Faculty of Health Sciences - The Arctic University of Norway, Tromsø, Norway , Rudge, Marilza Vieira Cunha Botucatu Medical School - UNESP, Botucatu-SP, Brazil
Abstract :
PURPOSE:
To evaluate the contamination index of metals and pesticides in pregnant women, and to relate this to perinatal outcomes.
METHODS:
Descriptive, retrospective, exploratory study, developed from existing secondary data analyses at Level III maternity center. A total of 40 mothers with their newborns (NB), living in a rural area in Botucatu- Brazil and surrounding region. Blood samples from mothers and newborn were collected to determine the total contamination index for metals and pesticides. The concentrations of each metal and each pesticide were determined in blood samples of mothers and their newborns by Rudge's results. After obtaining these concentrations, the total contamination index in mother and NB was calculated, along with its correlation with clinical parameters of NB.
RESULTS:
There was no correlation (p> 0.05) between maternal contamination index with NB clinical parameters, and NB contamination index versus NB clinical parameters.
CONCLUSION:
The maternal contamination index of metals and pesticides was not related to perinatal outcomes, but it could be used as baseline parameter in future toxicological studies, regarding to long-term toxic characteristics as persistent organic pollutants, its long half-lives, bioacumulative, and expected to impose serious health effects on humans.
Keywords :
Pesticides , Metals , Contamination , Pregnancy