Title of article :
Comparative Analysis of the Different Dyes’ Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium
Author/Authors :
Zlatskiy, I. A Peoples Friendship University of Russia (RUDN University) - 6 Miklukho - Maklaya St - Moscow 117198 - Russia - State Institute of Genetic and Regenerative Medicine NAMS of Ukraine - 67 Vyshgorodska Str - Kyiv 04114 - Ukraine , Zlatska, A. V State Institute of Genetic and Regenerative Medicine NAMS of Ukraine - 67 Vyshgorodska Str. - Kyiv 04114 - Ukraine - Biotechnology Laboratory Ilaya Regeneration - Medical Company Ilaya - Kiev - Ukraine , Antipova, N. V Shemyakin - Ovchinnikov Institute of Bioorganic Chemistry - RAS - Moscow - Russia - Peoples Friendship University of Russia (RUDN University) - 6 Miklukho - Maklaya St - Moscow 117198 - Russia , Dolenko, S. A Institute of Colloid and Water Chemistry - National Academy of Sciences of Ukraine - Kyiv 03680 - Ukraine , Gordiienko, I.M RE Kavetsky Institute of Experimental Pathology - Oncology and Radiobiology - National Academy of Sciences of Ukraine - Kyiv - Ukraine , Gubar, O. S Biotechnology Laboratory Ilaya Regeneration - Medical Company Ilaya - Kiev - Ukraine , Vasyliev, R. G State Institute of Genetic and Regenerative Medicine NAMS of Ukraine - 67 Vyshgorodska Str - Kyiv 04114 - Ukraine , Zubov, D. A State Institute of Genetic and Regenerative Medicine NAMS of Ukraine - 67 Vyshgorodska Str. - Kyiv 04114 - Ukraine - Biotechnology Laboratory Ilaya Regeneration - Medical Company Ilaya - Kiev - Ukraine , Novikova, S. N State Institute of Genetic and Regenerative Medicine NAMS of Ukraine - 67 Vyshgorodska Str - Kyiv 04114 - Ukraine , Syroeshkin, A. V Peoples Friendship University of Russia (RUDN University) - 6 Miklukho - Maklaya St - Moscow 117198 - Russia
Pages :
8
From page :
1
To page :
8
Abstract :
In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally sensitive to the D/H ratios in the culture medium (system) as well as to the different cell types (cancer vs normal cells).
Keywords :
laser diffraction , biological dyes , D/H ratios , culture medium (system) , cancer vs normal cells , Cancer Cell Viability , Human Normal , Culture Medium
Journal title :
The Scientific World Journal
Serial Year :
2020
Full Text URL :
Record number :
2615601
Link To Document :
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