Title of article
Heat Stress-Induced DNA Damage
Author/Authors
Kantidze, O.L. Institute of Gene Biology - Russian Academy of Sciences, russia , Velichko, A.K. Institute of Gene Biology - Russian Academy of Sciences, russia , Luzhin, A.V. Institute of Gene Biology - Russian Academy of Sciences, russia , Razin, S.V. Institute of Gene Biology - Russian Academy of Sciences, russia
Pages
4
From page
75
To page
78
Abstract
Although the heat-stress response has been extensively studied for decades, very little is known about its effects on nucleic acids and nucleic acid-associated processes. This is due to the fact that the research has fo-cused on the study of heat shock proteins and factors (HSPs and HSFs), their involvement in the regulation of transcription, protein homeostasis, etc. Recently, there has been some progress in the study of heat stress effects on DNA integrity. In this review, we summarize and discuss well-known and potential mechanisms of formation of various heat stress-induced DNA damage.
Farsi abstract
فاقد چكيده فارسي
Keywords
heat shock , DNA repair , DNA damage , DNA replication , topoisomerase
Journal title
Acta Naturae
Serial Year
2016
Full Text URL
Record number
2616045
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