Title of article
Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP?
Author/Authors
Stovicek, Jan Department of Internal Medicine - Charles University in Prague - 2nd Faculty of Medicine - University Hospital Motol in Prague, Czech Republic , Hlava, Stepan Department of Internal Medicine - Charles University in Prague - 2nd Faculty of Medicine - University Hospital Motol in Prague, Czech Republic , Keil, Radan Department of Internal Medicine - Charles University in Prague - 2nd Faculty of Medicine - University Hospital Motol in Prague, Czech Republic , Drabek, Jiri Department of Internal Medicine - Charles University in Prague - 2nd Faculty of Medicine - University Hospital Motol in Prague, Czech Republic , Lochmannova, Jindra Department of Internal Medicine - Charles University in Prague - 2nd Faculty of Medicine - University Hospital Motol in Prague, Czech Republic , Koptova, Petra Department of Internal Medicine - Charles University in Prague - 2nd Faculty of Medicine - University Hospital Motol in Prague, Czech Republic , Wasserbauer, Martin Department of Internal Medicine - Charles University in Prague - 2nd Faculty of Medicine - University Hospital Motol in Prague, Czech Republic , Frybova, Barbora Department of Pediatric Surgery - Charles University in Prague - 2nd Faculty of Medicine, University Hospital Motol in Prague, Czech Republic , Snajdauf, Jiri Department of Pediatric Surgery - Charles University in Prague - 2nd Faculty of Medicine, University Hospital Motol in Prague, Czech Republic
Pages
5
From page
1
To page
5
Abstract
Over a twenty-year period, we performed 255 ERCP procedures in infants aged up to 1 year. ERCP was indicated in cholestatic infants with suspicion of biliary obstruction. The most common diagnosis was biliary atresia (48%), choledochal cysts (13%), and choledocholithiasis (4%). The procedure complication rate was 13.7%. Hyperamylasemia occurred in 12.9%. More severe complications were rare‐0.8% of ERCP procedure. There were no cases of postprocedural pancreatitis or death. Our study has proved that ERCP is a safe and reliable method in this age group. Its high specificity and negative predictive value for extrahepatic biliary atresia can prevent unnecessary surgeries in patients with normal bile ducts or endoscopically treatable pathologies.
Keywords
Conjugated Hyperbilirubinemia , ERCP
Journal title
Canadian Journal of Gastroenterology and Hepatology
Serial Year
2021
Record number
2616100
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