Title of article :
Fluoroquinolone Resistance among Clonal Complex 1 Group B Streptococcus Strains
Author/Authors :
Neemuchwala, Alefiya Public Health Ontario Laboratory, Canada , Teatero, Sarah Public Health Ontario Laboratory, Canada , Patel, Samir N Public Health Ontario Laboratory, Canada , Fittipaldi, Nahuel Public Health Ontario Laboratory, Canada
Abstract :
Fluoroquinolone resistance in group B Streptococcus is increasingly being reported worldwide. Here, we correlated fluoroquinolone resistance with mutations in gyrA, gyrB, parC, and parE genes, identified by mining whole-genome sequencing (WGS) data of 190 clonal complex 1 group B Streptococcus strains recovered from patients with invasive diseases in North America. We report a high prevalence of fluoroquinolone resistance (12%) among GBS strains in our collection. Our approach is the first step towards accurate prediction of fluoroquinolone resistance from WGS data in this opportunistic pathogen.
Keywords :
Fluoroquinolone Resistance , Clonal Complex 1 Group B , Streptococcus Strains
Journal title :
Canadian Journal of Infectious Diseases and Medical Microbiology
