Author/Authors :
Fernandes Gomes, Monica Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) - Institute of Science and Technology - Sao Jose dos Campos Campus - Sao Paulo State University, Sao Paulo, SP, Brazil , Giovanni Bernardo Sichi, Luigi Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) - Institute of Science and Technology - Sao Jose dos Campos Campus - Sao Paulo State University, Sao Paulo, SP, Brazil , Chrystiane Giannasi, Lilian Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) - Institute of Science and Technology - Sao Jose dos Campos Campus - Sao Paulo State University, Sao Paulo, SP, Brazil , Oliveira Amorim, Jose Benedito Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) - Institute of Science and Technology - Sao Jose dos Campos Campus - Sao Paulo State University, Sao Paulo, SP, Brazil , Carlos da Rocha, João Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) - Institute of Science and Technology - Sao Jose dos Campos Campus - Sao Paulo State University, Sao Paulo, SP, Brazil , Yumi Koga-Ito, Cristiane Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) - Institute of Science and Technology - Sao Jose dos Campos Campus - Sao Paulo State University, Sao Paulo, SP, Brazil , Castillo Salgado, Miguel Angel Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) - Institute of Science and Technology - Sao Jose dos Campos Campus - Sao Paulo State University, Sao Paulo, SP, Brazil
Abstract :
Ectodermal dysplasia (ED) is a rare hereditary disorder affecting the development of ectoderm-derived organs and tissues. The
aim of this study was to describe phenotypic features and the therapeutic approach in dentistry among three patients with ED,
correlating their data with the literature. Additionally, to investigate the salivary gland disorders and their impacts on oral
microbiota, we performed salivary tests, including salivary flow rate, salivary buffering capacity, and concentration levels of
mutans streptococci, lactobacilli, and yeasts. All patients presented oligodontia, resulting in a significant masticatory dysfunction
and aesthetic impairment. The counts of mutans streptococci (n = 3) and yeasts (n =2) were high; on the other hand, the count of
lactobacilli (n = 3) was low. Therefore, salivary and microbiological tests showed that the patients with ED, particularly the
hypohidrotic type, presented a high risk of enamel caries and susceptibility to oral infections, which may be likely triggered by
reduction of salivary flow and/or possible immunological disorders.
