Author/Authors :
Pablo Zumárraga, juan Orthopedic Oncology Group - Instituto de Ortopedia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina - Universidade de São Paulo, São Paulo, SP, Brazil. , cartolano, ricardo Instituto de Ortopedia - Hospital das Clinicas HCFMUSP - Faculdade de Medicina - Universidade de São Paulo, São Paulo, SP, Brazil , tomio Kohara, marcelo Orthopedic Oncology Group - Instituto de Ortopedia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina - Universidade de São Paulo, São Paulo, SP, Brazil. , mathias baPtista, andré Orthopedic Oncology Group - Instituto de Ortopedia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina - Universidade de São Paulo, São Paulo, SP, Brazil. , gonçalves dos santos, FeliPe Orthopedic Oncology Group - Instituto de Ortopedia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina - Universidade de São Paulo, São Paulo, SP, Brazil. , Pires de camargo, olavo Orthopedic Oncology Group - Instituto de Ortopedia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina - Universidade de São Paulo, São Paulo, SP, Brazil.
Abstract :
Objective: Adamantinoma accounts for less than 1% of the primary
bone neoplasms. The tibia is the most affected bone and it is pre-
dominant in male patients between the second and third decades
of life. The objective of this study is to obtain epidemiological and
clinical information on patients with adamantinoma of the tibia treated
surgically between 1989 and 2016. Methods: Retrospective series
of seven patients diagnosed with adamantinoma of the tibia that
underwent surgery at the orthopedic oncology service of our hos-
pital. The information was obtained from the medical records and
histopathological reports of our institution. Results: A total of 2870
medical records with histological reports were evaluated. Seven
cases of adamantinoma of the tibia were included. The mean age
was 28.5 (17-49) years. We found a predominance of females (71.4%)
and the most affected side was the left one, with four cases (57.1%).
The biopsy revealed bone adamantinoma in four (57.1%) patients,
while the diagnosis of the other patients was confirmed after the
histological examination of the surgical specimen. All the patients
underwent surgery as definitive treatment. No positive margins were
reported. No local recurrence (LR) was reported and two patients
had distant metastasis (DM). Conclusion: The prognosis of survival
in cases of adamantinoma of the tibia is high. The rates of LR and
DM were low. Surgical treatment with extensive tumor resection is
the treatment of choice. Level of Evidence IV, Case Series.
Keywords :
Adamantinoma , Tibia , Bone neoplasms , Biopsy , Surgical oncology