Tp-e interval and Tp-e/QTc ratio: new choices for risk stratification of arrhythmic events in patients with hypertrophic cardiomyopathy

I read with a great interest the paper entitled “Tp-e interval and Tp-e/QTc ratio as novel surrogate markers for prediction of ventricular arrhythmic events in hypertrophic cardiomyopathy” by Akboğa et al. (1) published in The Anatolian Journal of Cardiology. In this novel investigation, the authors have shown that the Tp-e interval and Tp-e/QTc ratio were significantly longer and higher in patients with hypertrophic cardiomyopathy (HCM) than in controls. In addition, multivariate analysis revealed that these markers were associated with a higher risk of ventricular arrhythmic events (OR: 1.060; 95% CI: 1.005–1.117; p=0.012 and OR: 1.148; 95% CI: 1.086–1.204; p=0.049, respectively).