Title of article :
Crystal structure of 3-{5-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-1H-pyrazol-1-yl}indolin-2-one ethanol monosolvate
Author/Authors :
Rahman, Md. Lutfor University Malaysia Pahang - Faculty of Industrial Sciences and Technology,Malaysia , Kulkarni, Ajaykumar D. Department of Chemistry - KLS's Gogte Institute of Technology - Jnana Ganga, Udyambag, India , Yusoff, Mashitah Mohd. University Malaysia Pahang - Faculty of Industrial Sciences and Technology,Malaysia , Kwong, Huey Chong School of Chemical Sciences - Universiti Sains Malaysia, Malaysia , Quah, Ching Kheng X-ray Crystallography Unit - School of Physics - Universiti Sains Malaysia, Malaysia.
Abstract :
The title indolin-2-one compound, C28H23FN4O·C2H6O, crystallizes as a 1:1 ethanol solvate. The ethanol molecule is disordered over two positions with refined site occupancies of 0.560 (14) and 0.440 (14). The pyrazole ring makes dihedral angles of 84.16 (10) and 85.33 (9)° with the indolin-2-one and indole rings, respectively, whereas the dihedral angle between indolin-2-one and indole rings is 57.30 (7)°. In the crystal, the components are linked by N—H⋯O and O—H⋯O hydrogen bonds, forming an inversion molecule–solvate 2:2 dimer with R44(12) ring motifs. The crystal structure is consolidated by π–π interaction between pairs of inversion-related indolin-2-one rings [interplanar spacing = 3.599 (2) Å].
Keywords :
Malaysia , Penang , 11800 USM , Universiti Sains Malaysia , School of Physics , X-ray Crystallography Unit
Journal title :
Acta Crystallographica Section E: Crystallographic Communications
