Author/Authors :
Domachevsky, Liran Department of Nuclear Medicine - Assuta Medical Centers - Tel Aviv, Israel , Bernstine, Hanna Department of Nuclear Medicine - Assuta Medical Centers - Tel Aviv, Israel , Nidam, Meital Department of Nuclear Medicine - Assuta Medical Centers - Tel Aviv, Israel , Stein, Dan Department of Nuclear Medicine - Assuta Medical Centers - Tel Aviv, Israel , Goldberg, Natalia Department of Nuclear Medicine - Assuta Medical Centers - Tel Aviv, Israel , Stern, Dorit Department of Nuclear Medicine - Assuta Medical Centers - Tel Aviv, Israel , Abadi-Korek, Ifat Department of Nuclear Medicine - Assuta Medical Centers - Tel Aviv, Israel , Groshar, David Department of Nuclear Medicine - Assuta Medical Centers - Tel Aviv, Israel
Abstract :
To investigate same day 18F-FDG (Fluorodeoxyglucose) PET (Positron Emission Tomography)/MR (Magnetic
Resonance) test-retest repeatability of Standardized Uptake Value measurements normalized for body weight (SUV) and lean body
mass (SUL) in different locations in the liver. Methods. This prospective study was IRB approved with written informed consent
obtained. 35 patients (20 women and 15 men, 61 ± 11.2 years) that performed a whole-body 18F-FDG PET/MR followed by liverdedicated contrast-enhanced 18F-FDG PET/MR were included. SUV/L max, mean, and peak were measured inferior to, superior
to, and at the right portal vein and in the left lobe of the liver. The coefficient of variation (CV) and intraclass correlation coefficient
(ICC) were calculated and Bland-Altman plots were obtained. Results. The variability for SUV/L’s measurements was lowest inferior
to the portal vein (<9.2%) followed by measurements performed at the level of the portal vein (<14.6%).Conclusion.The area inferior
to the portal vein is the most reliable location for hepatic 18F-FDG uptake measurements on PET/MR.
Keywords :
18F-FDG , PET/MR , PET , ICC
