Title of article :
Crystal structure of ethyl 2-[2-(4-methylbenzoyl)-5-p-tolyl-1H-imidazol-1-yl]acetate
Author/Authors :
Yasmi Prabha,E. Arockia Jeya Department of Physics - University College of Engineering Nagercoil - Anna University, India , Kumar, S. Suresh Department of Physics - University College of Engineering Nagercoil - Anna University, India , Padala, Anil K. Medicinal Chemistry Division - Indian Institute of Integrative Medicine (IIIM) and Academy of Scientific and Innovative Research (AcSIR-IIIM), India , Ahmed,Qazi Naveed Medicinal Chemistry Division - Indian Institute of Integrative Medicine (IIIM) and Academy of Scientific and Innovative Research (AcSIR-IIIM), India , Athimoolama, S. Department of Physics - University College of Engineering Nagercoil - Anna University, India
Abstract :
In the title compound, C22H22N2O3, the plane of the five-membered ring is oriented at dihedral angles of 45.4 (1) and 52.5 (1)° to the phenyl rings. Furthermore, this ring makes an angle of 85.2 (2)° with the plane of the ethyl acetate substituent. The molecular structure is affected by an intramolecular C—H⋯O hydrogen bond between an H atom from the p-tolyl group and the carbonyl O atom of the acetate. The methyl group of the ethyl acetate residue is disordered over two sites with equal occupancies. The crystal structure features intermolecular C—H⋯O and C—H⋯N interactions. One of the C—H⋯O hydrogen bonds forms a C(5) chain motif extending along the a axis. In addition, C—H⋯N contacts form inversion dimers with R22(12) ring motifs, linking the imidazole ring system to the benzene ring of the p-tolyl substituent.
Keywords :
crystal structure , imidazole derivative , new synthesis , new synthesis , glycine methyl ester hydrochloride , 2-(4-methoxyphenyl)-2-oxoacetaldehyde
Journal title :
Acta Crystallographica Section E: Crystallographic Communications