Author/Authors :
Campos Tavares Junior, Wilson Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG) - Department of Surgery, Belo Horizonte, MG, Brazil , paulino, eduardo Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG) - Departamento de Anatomia Patológica, Belo Horizonte, MG, Brazil , angéliCa Baron magalhaes, maria Faculdade Evangélica do Paraná - Departamento de Cirurgia, Curitiba, PR, Brazil , guimarães gaBriCh FonseCa, ana Clara Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG) - Departamento de Anatomia Patológica, Belo Horizonte, MG, Brazil , Bernardo sanCio roCha rodrigues, João Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG) - Department of Surgery, Belo Horizonte, MG, Brazil , resende, vivian Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG) - Department of Surgery, Belo Horizonte, MG, Brazil
Abstract :
Objective: This study aimed to evaluate the dynamic contrast-en-
hanced magnetic resonance imaging (DCE-MRI) in the experimental
model of Achilles tendon injury. Methods: Twelve white male adults
New Zealand rabbits were divided into two groups, a group with resec-
tion of the central portion of the Achilles tendon (n = 8) and a control
group (n = 4). Dynamic contrast-enhanced magnetic resonance im-
aging (DCE-MRI) was performed 4 weeks after the surgical procedure,
followed by histological analysis of the tendons. Results: The main
finding of this study was the difference (p < 0.001) in peak contrast
enhancement on DCE-MRI, which demonstrated that the operated
group had greater contrast uptake. The operated tendons showed
histological disruption of their architecture, and cluttered appear-
ance of tendinous fibers, with vascular and fibroblast proliferations.
Conclusion: DCE-MRI is a technique with a potential to demonstrate
changes in the vascularity pattern of the Achilles tendon before and
after operation. DCE-MRI has a potential to be used in studies of
tendinosis diagnosis and surgical follow-up. Level of evidence II,
Experimental Study.
Keywords :
Magnetic Resonance Imaging , Perfusion , Tendon , Wound Healing
