Author/Authors :
Wang, Wei Department of Laboratory Medicine - Shanxi Provincial People’s Hospital, China , Wang, Li-fei Department of Tuberculosi - the Fifth People’s Hospital of Taiyuan, China , Liu, Yan-yan Department of Tuberculosi - the Fifth People’s Hospital of Taiyuan, China , Yang, Fang Department of Tuberculosi - the Fifth People’s Hospital of Taiyuan, China , Zhu, Lei Department of Laboratory Medicine - Children’s Hospital of Shanxi Province, China , Zhang, Xian-hui Department of Laboratory Medicine - Children’s Hospital of Shanxi Province, China
Abstract :
Objective
The objective of this study was to evaluate the change of the ratio of monocytes to lymphocytes in patients with active tuberculosis, such as to provide reference for clinical diagnosis and treatment.
Methods
All data were collected from the clinical database of The Fifth People's Hospital of Taiyuan, China. A total of 151 patients who had newly diagnosed active tuberculosis with tuberculosis therapy in hospital and 129 healthy controls were selected.
Results
Median ratio of monocytes to lymphocytes was 0.45 (IQR: 0.28–0.67) in patients before treatment and 0.32 (IQR: 0.25–0.46) on discharge (P < 0.001).
Conclusions
Ratio of monocytes to lymphocytes may be applied in diagnosis and the chemotherapeutic efficacy of active tuberculosis.
Keywords :
Ratio , Monocytes , Lymphocytes , Monitoring Tuberculosis Therapy
