Author/Authors :
Nourian, Anahid Department of Pharmacotherapy - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran , Khalili, Hossein Department of Pharmacotherapy - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Sofosbuvir may be a potential option in the treatment of COVID-19 based on the similarity between the replication mechanisms of the HCV and the coronavirus. According the limited experimental evidences, it is hypothesized that sofosbuvir might be a potential option to improve care of patients with COVID-19 especially at the start of the disease and before invasion of the virus into the lung parenchymal cells. Efficacy and safety of sofosbuvir in treatment of COVID-19 may be considered in future clinical studies. (www.actabiomedica.it)