Author/Authors :
Genovese, Cristina Department of Biomedical and Dental Sciences and Morphofunctional Imaging - University of Messina, Messina, Italy , La Fauci, Vincenza Department of Biomedical and Dental Sciences and Morphofunctional Imaging - University of Messina, Messina, Italy , D’Amato, Smeraldo Department of Biomedical and Dental Sciences and Morphofunctional Imaging - University of Messina, Messina, Italy , Squeri, Andrea Department of Human Pathology of the adult and developmental age Gaetano Barresi - University of Messina, Messina, Italy , Anzalone, Carmelina Department of Biomedical and Dental Sciences and Morphofunctional Imaging - University of Messina, Messina, Italy , Bruno Costa, Gaetano Department of Biomedical and Dental Sciences and Morphofunctional Imaging - University of Messina, Messina, Italy , Fedele, Francesco Department of Biomedical and Dental Sciences and Morphofunctional Imaging - University of Messina, Messina, Italy , Squeri, Raffaele Department of Biomedical and Dental Sciences and Morphofunctional Imaging - University of Messina, Messina, Italy
Abstract :
Healthcare-associated infections (HAIs) are the most frequent and severe complication acquired in healthcare settings with high impact in terms of morbidity, mortality and costs. Many bacteria could be im-plicated in these infections, but, expecially multidrug resistance bacteria could play an important role. Many microbial typing technologies have been developed until to the the bacterial whole-genome sequencing and the choice of a molecular typing method therefore will depend on the skill level and resources of the labora-tory and the aim and scale of the investigation. In several studies the molecular investigation of pathogens involved in HAIs was performed with many microorganisms identified as causative agents such as Pseu-domonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Clostridium difficile, Acinetobacter spp., Enterobacter spp., Enterococcus spp., Staphylococcus aureus and several more minor species. Here, we will describe the most and least frequently reported clonal complex, sequence types and ribotypes with their worldwide geographic distribution for the most important species involved in HAIs. (www.actabiomedica.it)
