Title of article :
Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis
Author/Authors :
Angela Tosca, Maria Allergy Center - Istituto Giannina Gaslini, Genoa, Italy , Olcese, Roberta Allergy Center - Istituto Giannina Gaslini, Genoa, Italy , Marinelli, Guido Allergy Center - Istituto Giannina Gaslini, Genoa, Italy , Papale, Maria Department of Clinical and Experimental Medicine - University of Catania, Catania , Maria Zicari, Anna Pediatrics Department - Umberto I Hospital - Sapienza University, Roma, Italy , Marseglia, Gianluigi Department of Pediatrics - Fondazione IRCCS Policlinico San Matteo -University of Pavia, Pavia, Italy , Ciprandi, Giorgio Allergy Clinic, Villa Montallegro, Genoa, Italy
Abstract :
Antihistamines are the cornerstone treatment of allergic rhinitis (AR). To quantify the antihis-taminic consume is particularly relevant in clinical practice, since a remarkable use is usually associated with severe symptoms. The aim of the study was to measure the use of antihistamines in two groups of children suffering from AR. The first group took a course of a nutraceutical (Lertal®) before the observation (active group, AG); a second one was considered as control (control group, CG). Both groups took antihistamines on demand. The children were visited at baseline and after 1 year. The number of days of antihistaminic use was the primary outcome. Children in AG had a significant reduced number of antihistamines use in com-parison with CG (p=0.008). In conclusion, the current study showed that a course with a multicomponent nutraceutical could reduce the use of symptomatic antihistamines in children with allergic rhinoconjuncti-vitis. (www.actabiomedica.it)
Keywords :
allergic rhinitis , antihistamines , children , medication use , nutraceutical
