Author/Authors :
Vicentine, Fernando Pompeu Piza Universidade Federal de São Paulo (UNIFESP), Brazil , Gonzalez, Adriano Miziara Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Beninni, Barbara Burza Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Azevedo, Ramiro Anthero de Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Linhares, Marcelo Moura Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Goldenberg, Alberto Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Lopes, Gaspar de Jesus Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Martins, Jose Luiz Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil , Salzedas, Alcides Augusto Department of Surgery - UNIFESP, Sao Paulo-SP, Brazil
Abstract :
Purpose:
To analyze the use of this sponge in pediatric patients undergoing split-liver transplantation.
Methods:
Retrospective study, including 35 pediatric patients undergoing split-liver transplantation, divided into two groups according to the use of the sponge: 18 patients in Group A (no sponge) and 17 in Group B (with sponge).
Results:
The characteristics of recipients and donors were similar. We observed greater number of reoperation due to bleeding in the wound area in Group A (10 patients - 55.5%) than in Group B (3 patients - 17.6%); p = 0.035. The median volume of red blood cells transfused in Group A was significantly higher (73.4 ± 102.38 mL/kg) than that in Group B (35.1 ± 41.67 mL/kg); p = 0.048. Regarding bile leak there was no statistical difference.
Conclusion:
The use of the human fibrinogen and thrombin sponge, required lower volume of red blood cell transfusion and presented lower reoperation rates due to bleeding in the wound area.
Keywords :
Liver Transplantation , Homeostasis , Fibrinogen , Thrombin
