Title of article :
A fractal physics explanation for acute thrombotic occlusion in an apparently healthy coronary artery
Author/Authors :
Tesloianu, Nicolae Dan Department of Cardiology - “St. Spiridon” University Hospital - Iasi - Romania , Nedelciuc, Igor Institute of Cardiovascular Disease “G.I.M. Georgescu” - Iasi - Romania , Ghizdovat, Vlad Department of Biophysics and Medical Physics - “Grigore T. Popa” University of Medicine and Pharmacy - Faculty of Medicine - Iasi - Romania , Agop, Maricel Lasers - Atoms and Molecules Physics Laboratory - University of Science and Technology , Lupascu- Ursulescu, Corina Department of Radiology - Grigore T. Popa” University of Medicine and Pharmacy - Faculty of Medicine - Iasi-Romania
Abstract :
The acute arterial occlusion of an artery that has no significant preexistent lesions leads to dramatic consequences
due to the lack of collateral substitutive circulation, as this kind
of circulation usually develops within years in the presence of
hemodynamic significant stenosis (1).
Classical models which explain this phenomenon take into
account the cracking of an intimal atheroma plaque, the activation of the prothrombogenic cascade through the denudation of
the endothelium, and the formation of a completely occlusive
thrombus in certain circumstances (2, 3). At least one counterargument should be considered: Why does an occlusive
thrombus form so quickly in the absence of a stenosis when the
sanguine flux is unaltered? Why the “wash-out’’ phenomenon
does not appear?
Keywords :
fractal physics explanation , acute thrombotic occlusion , apparently healthy coronary artery
Journal title :
The Anatolian Journal of Cardiology: Andolu Kardiyoloji Dergisi
