Author/Authors :
HUSTED, Henrik Orthopedics Department - Copenhagen University Hospital Hvidovre, Copenhagen , JØRGENSEN, Christoffer C The Lundbeck Foundation Center for Fast-track Hip and Knee Replacement , GROMOV, Kirill rthopedics Department - Copenhagen University Hospital Hvidovre, Copenhagen , KEHLET, Henrik The Lundbeck Foundation Center for Fast-track Hip and Knee Replacement
Abstract :
Background and purpose — Body mass index (BMI) outside the
normal range possibly affects the perioperative morbidity and
mortality following total hip arthroplasty (THA) and total knee
arthroplasty (TKA) in traditional care programs. We determined
perioperative morbidity and mortality in such patients who were
operated with the fast-track methodology and compared the
levels with those in patients with normal BMI.
Patients and methods — This was a prospective observational
study involving 13,730 procedures (7,194 THA and 6,536 TKA
operations) performed in a standardized fast-track setting. Com-
plete 90-day follow-up was achieved using national registries and
review of medical records. Patients were grouped according to
BMI as being underweight, of normal weight, overweight, obese,
very obese, and morbidly obese.
Results — Median length of stay (LOS) was 2 (IQR: 2–3) days
in all BMI groups.
30-day re-admission rates were around 6% for both THA
(6.1%) and TKA (5.9%), without any statistically signifi cant dif-
ferences between BMI groups in univariate analysis (p > 0.4), but
there was a trend of a protective effect of overweight for both
THA (p = 0.1) and TKA (p = 0.06).
90-day re-admission rates increased to 8.6% for THA and 8.3%
for TKA, which was similar among BMI groups, but there was
a trend of lower rates in overweight and obese TKA patients (p
= 0.08 and p = 0.06, respectively). When we adjusted for preop-
erative comorbidity, high BMI in THA patients (very obese and
morbidly obese patients only) was associated with a LOS of > 4
days (p = 0.001), but not with re-admission. No such relationship
existed for TKA.
Interpretation — A fast-track setting resulted in similar length
of hospital stay and re-admission rates regardless of BMI, except
for very obese and morbidly obese THA patients.