Title of article :
Amphiphilic Polymer-Modified Uniform CuFeSe2 Nanoparticles for CT/MR Dual-Modal Imaging
Author/Authors :
Wu, Min Department of Radiology - The Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China , Fu, Shaozhi Department of Oncology - The Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China , Shu, Jian Department of Radiology - The Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China , Yu, Kequan Department of Surgery - The First Affiliated Hospital of Chongqing Medical University - Chongqing, China
Abstract :
Recently, magnetic photothermal nanomaterials have attracted much attention in the diagnosis and treatment of cancer. In this
study, we developed the ultrasmall magnetic CuFeSe2 nanoparticles for CT/MR dual-modal imaging. By controlling the reaction
time and condition, CuFeSe2 nanoparticles were synthesized by a simple directly aqueous method. After modification with
copolymer methoxy polyethylene glycol-polycaprolactone (MPEG-PCL), the obtained MPEG-PCL@CuFeSe2 nanoparticles
showed excellent water solubility, colloidal stability, and biocompatibility. In addition, they also exhibited superparamagnetism
and X-ray’s characteristics. For these properties, they will become ideal nanomaterials for CT/MR dual-modal imaging.
Keywords :
CT/MR , CuFeSe2 , Polymer , biological
Journal title :
Contrast Media and Molecular Imaging
