Title of article :
Is 18F-FDG PET/CT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis
Author/Authors :
Dahmarde, Hamid Department of Radiology - Faculty of Medicine - Zahedan University of Medical Sciences - Zahedan, Iran , Parooie, Fateme Zabol University of Medical Sciences - Zabol, Iran , Salarzaei, Morteza Zabol University of Medical Sciences - Zabol, Iran
Abstract :
The purpose of this study was to assess the diagnostic value of 18F-fluorodeoxy-glucose positron emission tomography/
computed tomography (FDG PET/CT) for detection of lymph node (LN) metastasis of colorectal cancer. Material and Methods. A
computerized search was performed to determine the relevant articles, published before October 2019. Stata Statistical Software,
version 15.0, and Meta-Disc (version 1.4) were used for the meta-analysis. Results. the sensitivity, specificity, positive likelihood
ratio, and negative likelihood ratio were 0.65, 0.75, 4.57, and 0.37 respectively. Studies that used SUVmax cut-off value ( ≤2.5)
demonstrated the best accuracy. Conclusion. 18F-FDG PET/CT shows a low sensitivity and high specificity for detecting the
metastasis of LNs in patients with newly diagnosed colorectal cancer.
Keywords :
18F-FDG , PET/CT , Lymph , CRC
Journal title :
Contrast Media and Molecular Imaging
