Author/Authors :
Fainardi, Valentina Cystic Fibrosis Unit - Children University Hospital, Parma , Longo, Francesco Department of Medicine and Surgery - Respiratory Disease and Lung Function Unit - University of Parma, Parma, Italy , Chetta, Alfredo Department of Medicine and Surgery - Respiratory Disease and Lung Function Unit - University of Parma, Parma, Italy , Esposito, Susanna Cystic Fibrosis Unit - Children University Hospital, Parma , Pisi, Giovanna Cystic Fibrosis Unit - Children University Hospital, Parma
Abstract :
The novel coronavirus SARS-CoV-2 was first identified in China in December 2019 and has since spread worldwide. People with Cystic Fibrosis (CF) have reduced survival mainly because of respiratory fail-ure due to chronic pulmonary infections. Therefore, CF patients should be considered to have an increased risk of developing severe manifestations in case of SARS-CoV-2 infection. Surprisingly, the results of recent studies concerning SARS-CoV-2 infection in patients with CF show that in these patients the infection rate was lower than that of the general population. Various factors have been considered to explain a possible protective effect of CF against SARS-CoV-2 infection