Author/Authors :
Ismed, Friardi The Laboratory of Natural Resource of Sumatra (LBS) and Faculty of Pharmacy, Indonesia , Farhan, Aulia The Laboratory of Natural Resource of Sumatra (LBS) and Faculty of Pharmacy, Indonesia , Bakhtiar, Amri The Laboratory of Natural Resource of Sumatra (LBS) and Faculty of Pharmacy, Indonesia , Zaini, Erizal The Laboratory of Natural Resource of Sumatra (LBS) and Faculty of Pharmacy, Indonesia , Nugraha, Yuda Prasetya Department of Chemistry and Materials Science - Tokyo Institute of Technology, Japan , Putra, Okky Dwichandra Department of Chemistry and Materials Science - Tokyo Institute of Technology, Japan
Abstract :
The title compound, C12H16O4 (systematic name: 2,4-dihydroxy-6-pentylbenzoic acid) is a natural product isolated from C. sanguinea (Schaer.) and is reported to have various pharmacological activities. The molecule is approximately planar (r.m.s. deviation for the non-H atoms = 0.096 Å) and features an intramolecular O—H⋯O hydrogen bond. In the crystal, each olivetolic acid molecule is connected to three neighbours via O—H⋯O hydrogen bonds, generating (10-1) sheets. This crystal is essentially isostructural with a related resorcinolic acid with a longer alkyl chain.
