Author/Authors :
Zhao, Yanhong Department of Nuclear Medicine - Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China , Xia, Yuxiao Department of Nuclear Medicine - Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China , Liu, Huipan Department of Nuclear Medicine - Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China , Wang, Zi Department of Nuclear Medicine - Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China , Chen, Yue Department of Nuclear Medicine - Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China , Zhang, Wei Department of Nuclear Medicine - Affiliated Hospital of Southwest Medical University - Luzhou - Sichuan, China
Abstract :
To preliminarily evaluate the feasibility and potential of using 68Ga-PSMA-11 PET/CT in evaluating the function of
salivary glands and lacrimal glands in comparison with 99mTc-pertechnetate (99mTcO −
4 ) salivary gland scintigraphy (SGS).
Methods. A retrospective study was performed in 15 patients with dierent degrees of xerostomia and suspected salivary gland
dysfunction. Each patient underwent 68Ga-PSMA-11 PET/CT first and SGS the next day, and the findings of both scans were
compared. Results. The results of 68Ga-PSMA-11 PET/CT and SGS were consistent in 12/15 patients (80%) and were inconsistent
in the remaining patients (20%). For 5 (33.3%) of 15 patients, 68Ga-PSMA-11 PET/CT provided more information than did SGS.
Additionally, 68Ga-PSMA-11 PET/CT corrected the misdiagnosis by SGS for 1 patient. Conclusions. 68Ga-PSMA-11 PET/CT is a
potentially useful imaging tool for evaluating the function of salivary glands and lacrimal glands. 68Ga-PSMA-11 PET/CT can be a
promising supplement to SGS, and its clinical value deserves further study.
Keywords :
68Ga , PET/CT , 99mTcO4 , Preliminary , AECG
